Have a male patient suffering from depression, anxiety, and/or fatigue? Skip the SSRI and check their total and free testosterone levels first. Low testosterone will make a man feel awful with symptoms of depression, fatigue, insomnia, low motivation, low libido, and anxiety. Antidepressants simply mask the symptoms where testosterone replacement therapy treats the underlying issue! Try it next time you have a male complaining of depression and anxiety, you might be surprised.