We are taught that taking metronidazole with alcohol could cause a disulfiram-like reaction: N+V, dizziness, headache, abdominal discomfort…. basically, hangover-like symptoms.
But, according to one study, metronidazole does not interact with alcohol in the healthy adult. The risk is theoretical. Anecdotally, I know many patients who have drank ETOH and taken metronidazole without ill effect. For that reason, I don’t even bring it up during visits and have never heard of a reported ill effect. Additionally, my sister was on it and drank wine… nothing!
Obviously, use your own clinical judgement, but there are many “medical myths” that have no evidence to support them.