Clinical Pearl Wednesday #65

Feet Gout Pain Foot Human Anomaly  - cnick / Pixabay
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Have a patient with recurrent gout who also has hypertension or hyperlipidemia?

Consider putting them on these two medications that have potent uric acid reducing effects.

  1. Losartan has been shown to decrease serum levels of uric acid by approximately 10-15%.
  2. Fenofibrate has been shown to decrease serum levels of uric acid by approximately 20-30%.

If the patient has primary indications for either drug and has issues with gout, the addition of these 2 medications could prove to act as an effective gout prophylactic treatment.

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