Do you have a patient with ongoing nausea and vomiting? Have you tried the common medications like Zofran or Phenergan? Don’t forget about Reglan!

Metoclopramide, or Reglan, is often a forgotten medication that works fantastic for intractable nausea and vomiting. I have seen it work wonders in individuals with migraine associated nausea and vomiting, cyclic nausea and vomiting, and gastric paresis.

It can be given either IM or PO in the outpatient setting. It is best to start at 5mg but giving a dose of 10mg for severe nausea and vomiting works great. Usually, just one dose is all that is needed to “knock it out” so the patient can resume more common medications like Zofran.

Reglan is well tolerated, but it can cause tardive dyskinesia with prolonged use, so be sure to only use it sparingly with your patients!

As always, use your best clinical judgement!